Successful treatment of syringotropic CD8+ mycosis fungoides accompanied by hypohidrosis with vorinostat and retinoids

Aya Kakizaki; Taku Fujimura; Masato Mizuashi; Akiko Watabe; Yumi Kambayashi; Setsuya Aiba

doi:10.1111/j.1440-0960.2012.00944.x

Successful treatment of syringotropic CD8+ mycosis fungoides accompanied by hypohidrosis with vorinostat and retinoids

Aya Kakizaki, Taku Fujimura, Masato Mizuashi, Akiko Watabe, Yumi Kambayashi, Setsuya Aiba

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

We describe a 34-year-old Japanese man with syringotropic CD8+ mycosis fungoides (MF) accompanied by hypohidrosis who was treated with vorinostat and retinoids. Interestingly, immunohistochemical staining for dermcidin revealed a decrease of sweat in the eccrine glands, and a sweat test by the iodine starch method proved hypohidrosis in the MF-affected areas. Six months after treatment with this combination therapy, the patient's advanced MF was under control.

Original language	English
Pages (from-to)	e82-e84
Journal	Australasian Journal of Dermatology
Volume	54
Issue number	4
DOIs	https://doi.org/10.1111/j.1440-0960.2012.00944.x
Publication status	Published - 2013 Nov

Keywords

CD8 + MF
hypohidrosis
syringotropism
vorinostat

ASJC Scopus subject areas

Dermatology

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10.1111/j.1440-0960.2012.00944.x

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title = "Successful treatment of syringotropic CD8+ mycosis fungoides accompanied by hypohidrosis with vorinostat and retinoids",

abstract = "We describe a 34-year-old Japanese man with syringotropic CD8+ mycosis fungoides (MF) accompanied by hypohidrosis who was treated with vorinostat and retinoids. Interestingly, immunohistochemical staining for dermcidin revealed a decrease of sweat in the eccrine glands, and a sweat test by the iodine starch method proved hypohidrosis in the MF-affected areas. Six months after treatment with this combination therapy, the patient's advanced MF was under control.",

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AU - Kakizaki, Aya

AU - Fujimura, Taku

AU - Mizuashi, Masato

AU - Watabe, Akiko

AU - Kambayashi, Yumi

AU - Aiba, Setsuya

PY - 2013/11

Y1 - 2013/11

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AB - We describe a 34-year-old Japanese man with syringotropic CD8+ mycosis fungoides (MF) accompanied by hypohidrosis who was treated with vorinostat and retinoids. Interestingly, immunohistochemical staining for dermcidin revealed a decrease of sweat in the eccrine glands, and a sweat test by the iodine starch method proved hypohidrosis in the MF-affected areas. Six months after treatment with this combination therapy, the patient's advanced MF was under control.

KW - CD8 + MF

KW - hypohidrosis

KW - syringotropism

KW - vorinostat

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Successful treatment of syringotropic CD8+ mycosis fungoides accompanied by hypohidrosis with vorinostat and retinoids

Abstract

Keywords

ASJC Scopus subject areas

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