Successful Treatment of Segmental Vitiligo in Children with the Combination of 1-mm Minigrafts and Phototherapy

Kenichiro Tsuchiyama, Akiko Watabe, Anna Sadayasu, Nobue Onodera, Yutaka Kimura, Setsuya Aiba

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Background: Minigrafts using a 1-mm biopsy punch (1-mm minigrafts) are being increasingly used to treat vitiligo. However, there have been few reports of the use of 1-mm minigrafts in pediatric patients. Objective: To examine the effectiveness of combination therapy with 1-mm minigrafts and phototherapy in children with segmental vitiligo. Methods: Minigrafts were placed in 13 patients aged ≤16 years with segmental vitiligo. Following surgery, 11 patients underwent irradiation with excimer laser light and 2 with narrow-band ultraviolet B light. Results: A mean repigmentation of 81.6% was obtained. A particularly high mean repigmentation of 87.9% was seen in patients aged ≤12 years, indicating greater efficacy in these patients than in patients aged ≥13 years (mean, 67.5%). Although a transient cobblestone appearance occurred as an adverse effect, it improved over time. Conclusions: Combined treatment of segmental vitiligo with 1-mm minigrafts and phototherapy can be performed safely and is highly effective in young patients.

Original languageEnglish
Pages (from-to)237-241
Number of pages5
JournalDermatology
Volume232
Issue number2
DOIs
Publication statusPublished - 2016 Apr 1

Keywords

  • 1-mm minigrafts
  • Phototherapy
  • Segmental vitiligo

ASJC Scopus subject areas

  • Dermatology

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