Substance P-like immunoreactivity in the pulp-dentine zone of human molar teeth demonstrated by indirect immunofluorescence

S. Wakisaka, H. Ichikawa, T. Nishimoto, S. Matsuo, K. Yamamoto, T. Nakata, M. Akai

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Freshly-extracted human third molars were fixed in Zamboni fixative, demineralized with the mixture of EDTA and the fixative; substance P-like immunoreactivity (SPLI) was revealed by the indirect immunofluorescence teachnique of Coons. Substance P (SP) was observed in the pulp-dentine zone and the dental pulp. Some of SP-containing fibres ended at the odontoblast layer and did not reach the predentine; others terminated at the predentine surface or penetrated into the predentine. In the predentine, some of SP fibres accompanied odontoblast processes and ended near the mineralized dentine; others changed course transversely at various levels.

Original languageEnglish
Pages (from-to)73-75
Number of pages3
JournalArchives of Oral Biology
Volume29
Issue number1
DOIs
Publication statusPublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Dentistry(all)
  • Cell Biology

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