Study of the diagnostic value of the HB index (IHb) to detect Helicobacter pylori infection

Shigemitsu Aida; Shigeru Asaki; Hitoshi Sekine; Shuichi Ohara; Tooru Shimosegawa

Study of the diagnostic value of the HB index (IHb) to detect Helicobacter pylori infection

Shigemitsu Aida, Shigeru Asaki, Hitoshi Sekine, Shuichi Ohara, Tooru Shimosegawa

MED - Medical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND & AIMS : It is considered that the Hb index (IHb) is correlated with the mucosal Hemoglobin density. The aim of this study was to investigate the use of the IHb to detect H. pylori infection. METHODS : Firstly, we estimated the best condition of the IHb. Secondaly, we evaluated the relationship between the IHb, histological examination and mucosal blood flow. Considering the basal estimation, we investigated the IHb in 30 patients. RESULTS : We found the most suitable photo-condition was within 10mm distance from gastric mucosa. And the IHb was correlated with the density of the micro-vessels in the gastric mucosa using immunohistochemistry, but IHb did not depend on the mucosal blood flow. In addition, we determined the cut off index of the IHb was 62 for diagnosis of H. pylori infection. We showed the sensitivity was 93.3%, specificity was 80% and that the accuracy was 86.7%. CONCLUSIONS : IHb was simple and available method for the diagnosis of H. pylori infected gastric mucosa.

Original language	English
Pages (from-to)	925-933
Number of pages	9
Journal	GASTROENTEROLOGICAL ENDOSCOPY
Volume	43
Issue number	5
Publication status	Published - 2001 May 1

Keywords

H. pylori
Hb index (IHb)

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Gastroenterology

Cite this

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title = "Study of the diagnostic value of the HB index (IHb) to detect Helicobacter pylori infection",

abstract = "BACKGROUND & AIMS : It is considered that the Hb index (IHb) is correlated with the mucosal Hemoglobin density. The aim of this study was to investigate the use of the IHb to detect H. pylori infection. METHODS : Firstly, we estimated the best condition of the IHb. Secondaly, we evaluated the relationship between the IHb, histological examination and mucosal blood flow. Considering the basal estimation, we investigated the IHb in 30 patients. RESULTS : We found the most suitable photo-condition was within 10mm distance from gastric mucosa. And the IHb was correlated with the density of the micro-vessels in the gastric mucosa using immunohistochemistry, but IHb did not depend on the mucosal blood flow. In addition, we determined the cut off index of the IHb was 62 for diagnosis of H. pylori infection. We showed the sensitivity was 93.3%, specificity was 80% and that the accuracy was 86.7%. CONCLUSIONS : IHb was simple and available method for the diagnosis of H. pylori infected gastric mucosa.",

keywords = "H. pylori, Hb index (IHb)",

author = "Shigemitsu Aida and Shigeru Asaki and Hitoshi Sekine and Shuichi Ohara and Tooru Shimosegawa",

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T1 - Study of the diagnostic value of the HB index (IHb) to detect Helicobacter pylori infection

AU - Aida, Shigemitsu

AU - Asaki, Shigeru

AU - Sekine, Hitoshi

AU - Ohara, Shuichi

AU - Shimosegawa, Tooru

PY - 2001/5/1

Y1 - 2001/5/1

N2 - BACKGROUND & AIMS : It is considered that the Hb index (IHb) is correlated with the mucosal Hemoglobin density. The aim of this study was to investigate the use of the IHb to detect H. pylori infection. METHODS : Firstly, we estimated the best condition of the IHb. Secondaly, we evaluated the relationship between the IHb, histological examination and mucosal blood flow. Considering the basal estimation, we investigated the IHb in 30 patients. RESULTS : We found the most suitable photo-condition was within 10mm distance from gastric mucosa. And the IHb was correlated with the density of the micro-vessels in the gastric mucosa using immunohistochemistry, but IHb did not depend on the mucosal blood flow. In addition, we determined the cut off index of the IHb was 62 for diagnosis of H. pylori infection. We showed the sensitivity was 93.3%, specificity was 80% and that the accuracy was 86.7%. CONCLUSIONS : IHb was simple and available method for the diagnosis of H. pylori infected gastric mucosa.

AB - BACKGROUND & AIMS : It is considered that the Hb index (IHb) is correlated with the mucosal Hemoglobin density. The aim of this study was to investigate the use of the IHb to detect H. pylori infection. METHODS : Firstly, we estimated the best condition of the IHb. Secondaly, we evaluated the relationship between the IHb, histological examination and mucosal blood flow. Considering the basal estimation, we investigated the IHb in 30 patients. RESULTS : We found the most suitable photo-condition was within 10mm distance from gastric mucosa. And the IHb was correlated with the density of the micro-vessels in the gastric mucosa using immunohistochemistry, but IHb did not depend on the mucosal blood flow. In addition, we determined the cut off index of the IHb was 62 for diagnosis of H. pylori infection. We showed the sensitivity was 93.3%, specificity was 80% and that the accuracy was 86.7%. CONCLUSIONS : IHb was simple and available method for the diagnosis of H. pylori infected gastric mucosa.

KW - H. pylori

KW - Hb index (IHb)

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M3 - Article

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SN - 0387-1207

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JO - Gastroenterological Endoscopy

JF - Gastroenterological Endoscopy

IS - 5

ER -

Study of the diagnostic value of the HB index (IHb) to detect Helicobacter pylori infection

Abstract

Keywords

ASJC Scopus subject areas

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