Study of the diagnostic value of the HB index (IHb) to detect Helicobacter pylori infection

Shigemitsu Aida, Shigeru Asaki, Hitoshi Sekine, Shuichi Ohara, Tooru Shimosegawa

Research output: Contribution to journalArticlepeer-review


BACKGROUND & AIMS : It is considered that the Hb index (IHb) is correlated with the mucosal Hemoglobin density. The aim of this study was to investigate the use of the IHb to detect H. pylori infection. METHODS : Firstly, we estimated the best condition of the IHb. Secondaly, we evaluated the relationship between the IHb, histological examination and mucosal blood flow. Considering the basal estimation, we investigated the IHb in 30 patients. RESULTS : We found the most suitable photo-condition was within 10mm distance from gastric mucosa. And the IHb was correlated with the density of the micro-vessels in the gastric mucosa using immunohistochemistry, but IHb did not depend on the mucosal blood flow. In addition, we determined the cut off index of the IHb was 62 for diagnosis of H. pylori infection. We showed the sensitivity was 93.3%, specificity was 80% and that the accuracy was 86.7%. CONCLUSIONS : IHb was simple and available method for the diagnosis of H. pylori infected gastric mucosa.

Original languageEnglish
Pages (from-to)925-933
Number of pages9
Issue number5
Publication statusPublished - 2001 May 1


  • H. pylori
  • Hb index (IHb)

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology


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