Study of sterilization method for hybrid material for medical

Ayaka Tashiro, Yusuke Inoue, Takashi Isoyama, Itsuro Saito, Toshiya Ono, Masami Sato, Shintaro Hara, Terumi Yurimoto, Xinyang Li, Haruka Murakami, Yukino Kawase, Erina Maeno, Ko Imachi, Hiroshi Kumagai, Yusuke Abe

Research output: Contribution to journalArticlepeer-review


The purpose of this research is to establish sterilization method and preservation method for long time of hybrid material. Hybrid material was freeze dried and hybrid material was sterilized by four methods.The sterilization methods are autoclave, dry heat, ethylene oxide gas(EOG), and hydrogen peroxide gas plasma.We evaluate sterilization to compare structural change before and after the sterilization by microscopic observation.In autoclave and dry heat, hybrid materials were change color and transformation by heat.In these results, EOG sterilization is most suitable method of the hybrid material.Next, It is planed evaluate this sterilization method by cell culturing and animal experiment.

Original languageEnglish
Pages (from-to)O-555-O-556
JournalTransactions of Japanese Society for Medical and Biological Engineering
Publication statusPublished - 2014 Aug 17


  • Artificial material
  • Biomaterial
  • Freeze dry
  • Sterilization

ASJC Scopus subject areas

  • Biomedical Engineering


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