Studies toward the total synthesis of gymnocin A, a cytotoxic polyether: A highly convergent entry to the F-N ring fragment

Makoto Sasaki, Chihiro Tsukano, Kazuo Tachibana

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Matrix presented An efficient and highly convergent synthesis of the FGHIJKLMN ring fragment of gymnocin A, a cyctotoxic polycyclic ether isolated from the notorious red-tide forming dinoflagellate Gymnodinium mikimotoi, has been achieved. The present synthesis relied on extensive use of the B-alkyl Suzuki-Miyaura coupling reaction.

Original languageEnglish
Pages (from-to)1747-1750
Number of pages4
JournalOrganic letters
Volume4
Issue number10
DOIs
Publication statusPublished - 2002 May 16

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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