Studies on zoapatle, III. flavonoid glycosides from montanoa tomentosa ssp. tomentosa

The ethnomedical use of the tea prepared from the leaves of the zoapatle plant, Montanoa tomentosa, for the induction of menses and labor in the past 400 years in Mexico, the clinical evaluation of this preparation in human volunteers, the isolation, structural elucidation, and biological evaluation of zoapatanol, an oxepane diterpene claimed to be responsible for the action of the tea, as well as the synthesis of zoapatanol analogues and derivatives, have been the subjects of numerous reports. Summaries of these have recently been presented in review form (2–5).