Studies on the constituents of Swertia japonica MAKINO I. On the structures of new secoiridoid diglycosides

Masafumi Kikuchi, Masao Kikuchi

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Eight new secoiridoid diglycosides, 6′-O-α-L- arabinopyranosylswertiamarin (1), 3′-O-β-D-glucopyranosylswertiamarin (2), 4′-O-β-D-glucopyranosylswertiamarin (3), 3′-O-β-D- galactopyranosylswertiamarin (4), 6′-O-α-D- galactopyranosylswertiamarin (5), 6′-O-α-D- mannopyranosylswertiamarin (6), 6′-O-β-D-fructofuranosylswertiamarin (7) and 5″-O-β-D-glucopyranosylamaroswerin (12), were isolated, together with five known compounds from the whole plants of Swertia japonica MAKINO. The structures of the new compounds were elucidated on the basis of chemical and spectroscopic evidence. Compounds 6 and 7 are the first naturally occuring iridoid diglycosides having an α-D-mannopyranosyl unit and β-D-fructofuranosyl unit, respectively.

Original languageEnglish
Pages (from-to)1210-1214
Number of pages5
JournalChemical and Pharmaceutical Bulletin
Volume52
Issue number10
DOIs
Publication statusPublished - 2004 Oct 1

Keywords

  • Gentianaceae
  • Secoiridoid diglycoside
  • Swertia japonica
  • Swertiamarin biphenylcarboxylate

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

Fingerprint Dive into the research topics of 'Studies on the constituents of Swertia japonica MAKINO I. On the structures of new secoiridoid diglycosides'. Together they form a unique fingerprint.

  • Cite this