Studies on amino acid sequences of two isoforms of 17-kDa essential light chain of smooth muscle myosin from porcine aorta media

Yasushi Hasegawa, Yoshihisa Ueda, Michitoshi Watanabe, Fumi Morita

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21 Citations (Scopus)

Abstract

Amino acid sequences were analyzed for two isoforms of myosin essential light chain, LC17a and LC17b [Hasegawa. Y., Ueno, H., Hone, K., & Morit.a F. (1988) J. Biochem. 103, 15-18] from porcine aorta smooth muscle. Both LC17a and LC17b consisted of 150 amino acid residues and their N-terminal Cys residues were blocked by an acetyl group. The amino acid sequences of LC17a and LC17b were common from the N-terminal to Glu-141 and five amino acid substitutions were observed within the remaining C-terminal 9 residues. The amino acid sequences of LC17a and LC17b were identical to those deduced from the nucleotide sequences of bovine aortic cDNAs encoding the two isoforms [Lash, J. A., Helper, D.J., Kiug, M., Nicolozakes, A.W., & Hathaway, D.R. (1990) Nucleic Acids Res. 18, 7176].

Original languageEnglish
Pages (from-to)798-803
Number of pages6
JournalJournal of biochemistry
Volume111
Issue number6
DOIs
Publication statusPublished - 1992 Jun

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology

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