Structures of withametelin and isowithametelin, withanolides of datura metel leaves

Subhash C. Sinha; Sujata Kundu; Rakesh Maurya; Anil B. Ray; Yoshiteru Oshima; Anjana Bagchi; Hiroshi Hikino

doi:10.1016/S0040-4020(01)80076-4

Structures of withametelin and isowithametelin, withanolides of datura metel leaves

Subhash C. Sinha, Sujata Kundu, Rakesh Maurya, Anil B. Ray, Yoshiteru Oshima, Anjana Bagchi, Hiroshi Hikino

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

Structures of withametelin and isowithametelin, two novel hexacyclic withanolides isolated from the leaves of Datura metel, have been established as 1 and 2 respectively, on the basis of detailed spectral and chemical evidences. The facile transformation of withametelin to a ring A aromatic withanolide and some other interesting chemical transformations are described.

Original language	English
Pages (from-to)	2165-2176
Number of pages	12
Journal	Tetrahedron
Volume	45
Issue number	7
DOIs	https://doi.org/10.1016/S0040-4020(01)80076-4
Publication status	Published - 1989

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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abstract = "Structures of withametelin and isowithametelin, two novel hexacyclic withanolides isolated from the leaves of Datura metel, have been established as 1 and 2 respectively, on the basis of detailed spectral and chemical evidences. The facile transformation of withametelin to a ring A aromatic withanolide and some other interesting chemical transformations are described.",

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T1 - Structures of withametelin and isowithametelin, withanolides of datura metel leaves

AU - Sinha, Subhash C.

AU - Kundu, Sujata

AU - Maurya, Rakesh

AU - Ray, Anil B.

AU - Oshima, Yoshiteru

AU - Bagchi, Anjana

AU - Hikino, Hiroshi

PY - 1989

Y1 - 1989

N2 - Structures of withametelin and isowithametelin, two novel hexacyclic withanolides isolated from the leaves of Datura metel, have been established as 1 and 2 respectively, on the basis of detailed spectral and chemical evidences. The facile transformation of withametelin to a ring A aromatic withanolide and some other interesting chemical transformations are described.

AB - Structures of withametelin and isowithametelin, two novel hexacyclic withanolides isolated from the leaves of Datura metel, have been established as 1 and 2 respectively, on the basis of detailed spectral and chemical evidences. The facile transformation of withametelin to a ring A aromatic withanolide and some other interesting chemical transformations are described.

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