Structures of withametelin and isowithametelin, withanolides of datura metel leaves

Subhash C. Sinha, Sujata Kundu, Rakesh Maurya, Anil B. Ray, Yoshiteru Oshima, Anjana Bagchi, Hiroshi Hikino

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

Structures of withametelin and isowithametelin, two novel hexacyclic withanolides isolated from the leaves of Datura metel, have been established as 1 and 2 respectively, on the basis of detailed spectral and chemical evidences. The facile transformation of withametelin to a ring A aromatic withanolide and some other interesting chemical transformations are described.

Original languageEnglish
Pages (from-to)2165-2176
Number of pages12
JournalTetrahedron
Volume45
Issue number7
DOIs
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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