Structure of trehalostatin: A potent and specific inhibitor of trehalase

Toru Nakayama; Teruo Amachi; Sawao Murao; Takafumi Sakai; Takashi Shin; Peter T.M. Kenny; Takashi Iwashita; Michael Zagorski; Hajime Komura; Kyosuke Nomoto

doi:10.1039/C39910000919

Structure of trehalostatin: A potent and specific inhibitor of trehalase

Toru Nakayama, Teruo Amachi, Sawao Murao, Takafumi Sakai, Takashi Shin, Peter T.M. Kenny, Takashi Iwashita, Michael Zagorski, Hajime Komura, Kyosuke Nomoto

Research output: Contribution to journal › Article › peer-review

50 Citations (Scopus)

Abstract

A structural study of trehalostatin 1, a specific inhibitor of blowfly trehalase, revealed that 1 contains an unusual five-membered pseudocyclitol.

Original language	English
Pages (from-to)	919-921
Number of pages	3
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	14
DOIs	https://doi.org/10.1039/C39910000919
Publication status	Published - 1991 Dec 1
Externally published	Yes

ASJC Scopus subject areas

Molecular Medicine

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title = "Structure of trehalostatin: A potent and specific inhibitor of trehalase",

abstract = "A structural study of trehalostatin 1, a specific inhibitor of blowfly trehalase, revealed that 1 contains an unusual five-membered pseudocyclitol.",

author = "Toru Nakayama and Teruo Amachi and Sawao Murao and Takafumi Sakai and Takashi Shin and Kenny, {Peter T.M.} and Takashi Iwashita and Michael Zagorski and Hajime Komura and Kyosuke Nomoto",

year = "1991",

month = dec,

day = "1",

doi = "10.1039/C39910000919",

language = "English",

pages = "919--921",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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T1 - Structure of trehalostatin

T2 - A potent and specific inhibitor of trehalase

AU - Nakayama, Toru

AU - Amachi, Teruo

AU - Murao, Sawao

AU - Sakai, Takafumi

AU - Shin, Takashi

AU - Kenny, Peter T.M.

AU - Iwashita, Takashi

AU - Zagorski, Michael

AU - Komura, Hajime

AU - Nomoto, Kyosuke

PY - 1991/12/1

Y1 - 1991/12/1

N2 - A structural study of trehalostatin 1, a specific inhibitor of blowfly trehalase, revealed that 1 contains an unusual five-membered pseudocyclitol.

AB - A structural study of trehalostatin 1, a specific inhibitor of blowfly trehalase, revealed that 1 contains an unusual five-membered pseudocyclitol.

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U2 - 10.1039/C39910000919

DO - 10.1039/C39910000919

M3 - Article

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SN - 1359-7345

SP - 919

EP - 921

JO - Chemical Communications

JF - Chemical Communications

IS - 14

ER -

Structure of trehalostatin: A potent and specific inhibitor of trehalase

Abstract

ASJC Scopus subject areas

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