Abstract
Equal-opportunity dissolver: By attaching polyethylene glycol at its 5' end, DNA (PEG-DNA) can be solubilized in various organic solvents and was shown to form G-quadruplexes by CD spectroscopy. A complex containing iron(III) protoporphyrin IX (hemin) and G-quadruplex-forming PEG-DNA catalyzed an oxidative reaction in methanol (see scheme).
| Original language | English |
|---|---|
| Pages (from-to) | 6475-6479 |
| Number of pages | 5 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 51 |
| Issue number | 26 |
| DOIs | |
| Publication status | Published - 2012 Jun 25 |
Keywords
- DNA
- G-quadruplexes
- nucleic acids
- porphyrinoids
- structure-activity relationships
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)
Fingerprint Dive into the research topics of 'Structure formation and catalytic activity of DNA dissolved in organic solvents'. Together they form a unique fingerprint.
Cite this
Abe, H., Abe, N., Shibata, A., Ito, K., Tanaka, Y., Ito, M., Saneyoshi, H., Shuto, S., & Ito, Y. (2012). Structure formation and catalytic activity of DNA dissolved in organic solvents. Angewandte Chemie - International Edition, 51(26), 6475-6479. https://doi.org/10.1002/anie.201201111