Structure and properties characterization of amphiphilic dendrons modified lipid membrane

Jin Han, Yosuke Iimure, Yukihiro Okamoto, Keishi Suga, Hiroshi Umakoshi

Research output: Contribution to journalArticlepeer-review

Abstract

Coassembly of lipids and polyamidoamine amphiphilic dendrons (AD) is expected to provide desirable characteristics to drug delivery carriers. However, there have been few studies about structure and properties of these coassemblies. In this study, coassemblies (lipid-AD) were prepared by different generation and composition ratio of AD, and then the structure and their properties were characterized, especially fluidity and hydration state. In conclusion, generation of AD showed significant influence on coassembly structure and hydration state.

Original languageEnglish
Pages (from-to)187-190
Number of pages4
JournalChemistry Letters
Volume50
Issue number1
DOIs
Publication statusPublished - 2021

Keywords

  • Amphiphilic dendrimer
  • Hydration state
  • Lipid membrane

ASJC Scopus subject areas

  • Chemistry(all)

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