Strigolactones enhance competition between shoot branches by dampening auxin transport

Scott Crawford, Naoki Shinohara, Tobias Sieberer, Lisa Williamson, Gilu George, Jo Hepworth, Dörte Müller, Malgorzata A. Domagalska, Ottoline Leyser

    Research output: Contribution to journalArticle

    217 Citations (Scopus)

    Abstract

    Strigolactones (SLs), or their derivatives, were recently demonstrated to act as endogenous shoot branching inhibitors, but their biosynthesis and mechanism of action are poorly understood. Here we show that the branching phenotype of mutants in the Arabidopsis P450 family member, MAX1, can be fully rescued by strigolactone addition, suggesting that MAX1 acts in SL synthesis. We demonstrate that SLs modulate polar auxin transport to control branching and that both the synthetic SL GR24 and endogenous SL synthesis significantly reduce the basipetal transport of a second branch-regulating hormone, auxin. Importantly, GR24 inhibits branching only in the presence of auxin in the main stem, and enhances competition between two branches on a common stem. Together, these results support two current hypotheses: that auxin moving down the main stem inhibits branch activity by preventing the establishment of auxin transport out of axillary branches; and that SLs act by dampening auxin transport, thus enhancing competition between branches.

    Original languageEnglish
    Pages (from-to)2905-2913
    Number of pages9
    JournalDevelopment
    Volume137
    Issue number17
    DOIs
    Publication statusPublished - 2010 Sep 1

    Keywords

    • Arabidopsis
    • Auxin transport
    • Shoot branching
    • Strigolactone

    ASJC Scopus subject areas

    • Molecular Biology
    • Developmental Biology

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  • Cite this

    Crawford, S., Shinohara, N., Sieberer, T., Williamson, L., George, G., Hepworth, J., Müller, D., Domagalska, M. A., & Leyser, O. (2010). Strigolactones enhance competition between shoot branches by dampening auxin transport. Development, 137(17), 2905-2913. https://doi.org/10.1242/dev.051987