Stress response of subarachnoid hemorrhage to cardiac performance and intravascular volume evaluated by the Pulse Contour Cardiac Output (PiCCO) system

Tatsushi Mutoh, Ken Kazumata, Minoru Ajiki, Yuka Yokoyama, Juro Sakurai, Katsuyuki Asaoka, Satoshi Ushikoshi, Shunsuke Terasaka

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

The aim of this study was to investigate cardiac performance and volume status after subarachnoid hemorrhage (SAH). Hemodynamic and volumetric parameters including cardiac index (CI), intrathoracic blood volume index (ITBVI). and extravascular lung water index (EVLWI) were evaluated by single indicator transpulmonary thermodilution (PiCCO) from days 1 to 4 in 32 patients with SAH treated surgically or endovascularly within 24 hours. Higher CI and lower ITBVI values were observed after SAH. The mean value of CI was 5.2 l/min/m2 on day 1, which gradually decreased to 3.4 l/min/m 2 on day 4. The mean ITBVI value was 730 m1/m2 on day 1, which recovered to the reference range until day 4 by fluid administration aiming for normovolemia. Higher CI and lower ITBVI values were present in patients with poor clinical grade (WFNS grade IV, V) as compared with mild to moderate grade (I-II) (p < 0.05). Relationship between CI and SI were well correlated (r = 0.77, p < 0.0001). The results indicate that SAH predisposes patients to hyperdynamic and hypovolemic states associated with sympathetic hyperactivity, especially in patients with poor clinical grade. Bedside monitoring with the PiCCO system may be a powerful tool for the management of patients after SAH.

Original languageEnglish
Pages (from-to)163-168
Number of pages6
JournalNeurological Surgery
Volume35
Issue number2
Publication statusPublished - 2007 Feb 1
Externally publishedYes

Keywords

  • Cardiac output
  • Hemodynamics
  • Subarachnoid hemorrhage
  • Volume status

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Fingerprint

Dive into the research topics of 'Stress response of subarachnoid hemorrhage to cardiac performance and intravascular volume evaluated by the Pulse Contour Cardiac Output (PiCCO) system'. Together they form a unique fingerprint.

Cite this