Stereotactic body radiotherapy for pulmonary oligometastases from esophageal cancer: Results and prognostic factors

Takaya Yamamoto, Yuzuru Niibe, Yasuo Matsumoto, Yasuhiro Dekura, Ryoong Jin Oh, Hideomi Yamashita, Hisao Kakuhara, Masahiko Aoki, Keiichi Jingu

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Background/Aim: The aim of this multi-center retrospective study was to investigate the results of stereotactic body radiotherapy (SBRT) for pulmonary oligometastases from esophageal cancer. Patients and Methods: Oligometastases from the esophagus were identified from a dataset of a Japanese survey. The Kaplan-Meier method and Cox regression were applied to perform analyses. Results: A total of 114 patients with 132 pulmonary oligometastases were collected. The 3-year local control rate, freedom from further metastasis (FFFM) rate and overall survival (OS) rate were 70.2%, 25.3% and 37.5%, respectively. Performance status (PS) (PS 1 vs. PS 0, p<0.01), disease-free interval (p=0.03) and history of local therapy for metastasis (p=0.01) had significant relationships with FFFM and only PS was an independent prognostic factor for OS (PS 1 vs. PS 0, p=0.02; PS 2-3 vs. PS 0, p=0.04). Conclusion: SBRT for pulmonary oligometastases from esophageal cancer provided good local control and survival.

Original languageEnglish
Pages (from-to)2065-2072
Number of pages8
JournalAnticancer research
Volume40
Issue number4
DOIs
Publication statusPublished - 2020 Apr
Externally publishedYes

Keywords

  • Esophageal cancer
  • Oligo-recurrence
  • Oligometastases
  • Prognostic factor
  • Stereotactic body radiotherapy (SBRT)

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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