Stereoselective synthesis of the left wing of Caribbean ciguatoxin

Shuji Yamashita, Ryohei Uematsu, Masahiro Hirama

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Ciguatoxins, the principal causative toxins of ciguatera seafood poisoning, are potent toxic polycyclic ethers. In this paper, we report a stereoselective and secure route to the left wing of Caribbean ciguatoxin on the basis of a 6-exo radical cyclization strategy.

Original languageEnglish
Pages (from-to)6616-6626
Number of pages11
JournalTetrahedron
Volume67
Issue number35
DOIs
Publication statusPublished - 2011 Sep 2

Keywords

  • Caribbean ciguatoxin
  • Convergent synthesis
  • Polycyclic ether
  • Radical cyclization

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Stereoselective synthesis of the left wing of Caribbean ciguatoxin'. Together they form a unique fingerprint.

  • Cite this