Stereoselective synthesis of substituted tetrahydropyrans via domino olefin cross-metathesis/intramolecular oxa-conjugate cyclization

Haruhiko Fuwa, Kenkichi Noto, Makoto Sasaki

    Research output: Contribution to journalArticlepeer-review

    61 Citations (Scopus)

    Abstract

    (Figure Presented) A novel strategy for the stereoselective synthesis of substituted tetrahydropyrans has been developed on the basis of a domino olefin crossmetathesis/intramolecular oxa-conjugate cyclization catalyzed by the Hoveyda- Grubbs second-generation catalyst.

    Original languageEnglish
    Pages (from-to)1636-1639
    Number of pages4
    JournalOrganic letters
    Volume12
    Issue number7
    DOIs
    Publication statusPublished - 2010 Apr 2

    ASJC Scopus subject areas

    • Biochemistry
    • Physical and Theoretical Chemistry
    • Organic Chemistry

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