Treatment of α,β-unsaturated esters (1) with lithium amides [LiNPri2 and LiN(CH2Ph)SiMe3] followed by alkylation and elimination of the amino groups produced trisubstituted enoates (2) with high stereoselectivity.
|Number of pages||2|
|Journal||Journal of the Chemical Society, Chemical Communications|
|Publication status||Published - 1987 Dec 1|
ASJC Scopus subject areas
- Molecular Medicine