Stereocontrolled total synthesis of (+)-vinblastine

Satoshi Yokoshima, Toshihiro Ueda, Satoshi Kobayashi, Ayato Sato, Takeshi Kuboyama, Hidetoshi Tokuyama, Tohru Fukuyama

Research output: Contribution to journalArticlepeer-review

200 Citations (Scopus)

Abstract

A stereocontrolled total synthesis of (+)-vinblastine was accomplished, featuring preparations of the two indole units by means of a novel indole synthesis via radical cyclization of thioanilide, and a stereoselective coupling of these units.

Original languageEnglish
Pages (from-to)2137-2139
Number of pages3
JournalJournal of the American Chemical Society
Volume124
Issue number10
DOIs
Publication statusPublished - 2002 Mar 13

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Fingerprint Dive into the research topics of 'Stereocontrolled total synthesis of (+)-vinblastine'. Together they form a unique fingerprint.

Cite this