Stereocontrolled synthesis of the A/B-ring fragment of gambieric acid B: Reassignment of the absolute configuration of the polycyclic ether region

Haruhiko Fuwa, Tomomi Goto, Makoto Sasaki

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

(Chemical Equation Presented) Stereocontrolled synthesis of the A/B-ring fragment of the originally assigned structure of gambieric acid B and its possible diastereomers has been accomplished. Detailed comparison of their 1H and 13C NMR data with those of the corresponding moiety of the natural product culminated in a stereochemical reassignment of the absolute configuration of the polycyclic ether region of gambieric acid B.

Original languageEnglish
Pages (from-to)2211-2214
Number of pages4
JournalOrganic letters
Volume10
Issue number11
DOIs
Publication statusPublished - 2008 Jun 5

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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