Stepwise assembly of DNA tile on surfaces

Kotaro Somei, Shohei Kaneda, Teruo Fujii, Satoshi Murata

Research output: Chapter in Book/Report/Conference proceedingConference contribution


A method of solid-phase self-assembly for building DNA nanostructure in a microfluidic device is proposed in this paper. In this method, pre-assembled DNA lattice is anchored on solid surface, which gives nuclei for further growth of the lattice. Flushing out the solution around the nuclei by flow and replace it by different solution enables us stepwise self-assembly in a single chamber at the constant temperature. The results of experiment to verify feasibility of the proposed method will be shown.

Original languageEnglish
Title of host publicationDNA Computing - 13th International Meeting on DNA Computing, DNA13, Revised Selected Papers
Number of pages9
Publication statusPublished - 2008 Aug 27
Externally publishedYes
Event13th International Meeting on DNA Computing, DNA13 - Memphis, TN, United States
Duration: 2007 Jun 42007 Jun 8

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume4848 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349


Other13th International Meeting on DNA Computing, DNA13
Country/TerritoryUnited States
CityMemphis, TN


  • DNA tile
  • Microfluidic device
  • Self-assembly
  • Stepwise assembly

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)


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