Statins prevent pulsatile stretch-induced proliferation of human saphenous vein smooth muscle cells via inhibition of Rho/Rho-kinase pathway

Medicine & Life Sciences

• cerivastatin 100%
• rho-Associated Kinases 98%
• Saphenous Vein 89%
• Hydroxymethylglutaryl-CoA Reductase Inhibitors 77%
• Smooth Muscle Myocytes 70%
• Cell Proliferation 52%
• Mitogen-Activated Protein Kinases 31%
• hydroxyfasudil 30%
• Membranes 28%
• MAP Kinase Kinase 2 25%
• MAP Kinase Kinase 1 23%
• Phosphorylation 22%
• Y 27632 21%
• Mevalonic Acid 21%
• Retinoblastoma Protein 20%
• U 0126 20%
• Transplants 19%
• 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 18%
• Simvastatin 18%
• Vascular Remodeling 18%
• Phosphatidylinositol 3-Kinase 16%
• Vascular Diseases 15%
• Coronary Artery Bypass 15%
• Veins 13%
• Pressure 10%
• Incidence 7%
• Pharmaceutical Preparations 6%