Stabilities of 67Ga- and 111in-labeled transferrin In Vitro

Yosuke Ohtake, Akiko Maruko, Yoshikazu Kuwahara, Manabu Fukumoto, Yasuhito Ohkubo

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We attempted to develop a stable radiolabeled transferrin (Tf) useful in experimental studies related to Tf receptor. 67Ga and 111In were used as labeling radioisotopes. The results from gel chromatography, dialysis, and electrophoresis showed that 111 In-DTPA-Tf was the most stable among the radiolabeled Tfs examined in the present study. 111 In-DTPA-Tf was also the most stable radiolabeled transferrin in the blood.

Original languageEnglish
Pages (from-to)138-142
Number of pages5
JournalProtein and Peptide Letters
Volume16
Issue number2
DOIs
Publication statusPublished - 2009 Feb 1

Keywords

  • DTPA
  • Ga
  • In
  • Radiolabeling
  • Transferrin

ASJC Scopus subject areas

  • Structural Biology
  • Biochemistry

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    Ohtake, Y., Maruko, A., Kuwahara, Y., Fukumoto, M., & Ohkubo, Y. (2009). Stabilities of 67Ga- and 111in-labeled transferrin In Vitro. Protein and Peptide Letters, 16(2), 138-142. https://doi.org/10.2174/092986609787316298