Abstract
The authors report a 75-year-old woman with atypical sporadic Creutzfeldt-Jakob disease (CJD) characterized by MM1-type prion protein (PrP) (methionine homozygosity at codon 129 in the PrP gene and type-1 protease-resistant PrP) and PrP plaques. This patient is the first case of sporadic CJD with plaque-forming MM1-type PrP, suggesting either a shared prion strain with the plaque-forming subset of dural graft-associated CJD or shared host genetic factors that are unrelated to the PrP genotype.
Original language | English |
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Pages (from-to) | 514-517 |
Number of pages | 4 |
Journal | Neurology |
Volume | 60 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2003 Feb 11 |
ASJC Scopus subject areas
- Clinical Neurology