Abstract
The authors report a 75-year-old woman with atypical sporadic Creutzfeldt-Jakob disease (CJD) characterized by MM1-type prion protein (PrP) (methionine homozygosity at codon 129 in the PrP gene and type-1 protease-resistant PrP) and PrP plaques. This patient is the first case of sporadic CJD with plaque-forming MM1-type PrP, suggesting either a shared prion strain with the plaque-forming subset of dural graft-associated CJD or shared host genetic factors that are unrelated to the PrP genotype.
| Original language | English |
|---|---|
| Pages (from-to) | 514-517 |
| Number of pages | 4 |
| Journal | Neurology |
| Volume | 60 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2003 Feb 11 |
ASJC Scopus subject areas
- Clinical Neurology
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Cite this
Ishida, C., Kakishima, A., Okino, S., Furukawa, Y., Kano, M., Oda, Y., Nakanishi, I., Makifuchi, T., Kitamoto, T., & Yamada, M. (2003). Sporadic Creutzfeldt-Jakob disease with MM1-type prion protein and plaques. Neurology, 60(3), 514-517. https://doi.org/10.1212/01.WNL.0000044403.41041.A4