Spontaneous Regression of a Primary Cerebral Tumor Following Vasospasm Caused by Subarachnoid Hemorrhage Due to Rupture of an Intracranial Aneurysm: Case Report

Yoji Yamashita, Toshihiro Kumabe, Hiroyuki Shimizu, Masayuki Ezura, Teiji Tominaga

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A 40-year-old man demonstrated spontaneous regression of a malignant glioma following vasospasm caused by subarachnoid hemorrhage due to rupture of an intracranial aneurysm. The patient had been treated under a diagnosis of malignant glioma for 5 years. He presented with a ruptured aneurysm manifesting as subarachnoid hemorrhage. Single photon emission computed tomography with N-isopropyl-p-123I-iodoamphotamine and diffusion-weighted magnetic resonance (MR) imaging revealed severe flow reduction due to vasospasm in the bilateral temporoparietal cortical regions, including the tumor. MR imaging performed 5 months later showed marked tumor regression. The present case suggests that treatment targeting angiogenesis of malignant gliomas may be effective as a part of multimodality treatment.

Original languageEnglish
Pages (from-to)187-190
Number of pages4
JournalNeurologia medico-chirurgica
Volume44
Issue number4
DOIs
Publication statusPublished - 2004 Apr

Keywords

  • Malignant glioma
  • Spontaneous regression
  • Subarachnoid hemorrhage
  • Vasospasm

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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