Spontaneous alignment of a three-dimensional model of cultured endothelial cells under steady flow condition investigated using computational fluid mechanics

Takami Yamaguchi; Yasuhito Yamamoto

Spontaneous alignment of a three-dimensional model of cultured endothelial cells under steady flow condition investigated using computational fluid mechanics

Takami Yamaguchi, Yasuhito Yamamoto

MEN - Biomedical Engineering

Research output: Contribution to conference › Paper › peer-review

3 Citations (Scopus)

Abstract

Previous studies using three-dimensional computational fluid mechanical models of the endothelial cells under actual culture conditions as well as under the flow conditions on the arteriolar wall showed that there is a strong dependence of the local wall stress (WSS) distribution on the cellular shape factors and the cellular alignment. The present study simulated spontaneous random motions of the endothelial cells under actual culture conditions, and found that the endothelial cells aligned to the flow direction to reduce the wall shear stress at the summit of the cells.

Original language	English
Pages	511-512
Number of pages	2
Publication status	Published - 1995 Jan 1
Event	Proceedings of the 1995 Bioengineering Conference - Beever Creek, CO, USA Duration: 1995 Jun 28 → 1995 Jul 2

Other

Other	Proceedings of the 1995 Bioengineering Conference
City	Beever Creek, CO, USA
Period	95/6/28 → 95/7/2

ASJC Scopus subject areas

Engineering(all)

Cite this

Spontaneous alignment of a three-dimensional model of cultured endothelial cells under steady flow condition investigated using computational fluid mechanics. / Yamaguchi, Takami; Yamamoto, Yasuhito.

1995. 511-512 Paper presented at Proceedings of the 1995 Bioengineering Conference, Beever Creek, CO, USA.

Research output: Contribution to conference › Paper › peer-review

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abstract = "Previous studies using three-dimensional computational fluid mechanical models of the endothelial cells under actual culture conditions as well as under the flow conditions on the arteriolar wall showed that there is a strong dependence of the local wall stress (WSS) distribution on the cellular shape factors and the cellular alignment. The present study simulated spontaneous random motions of the endothelial cells under actual culture conditions, and found that the endothelial cells aligned to the flow direction to reduce the wall shear stress at the summit of the cells.",

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AB - Previous studies using three-dimensional computational fluid mechanical models of the endothelial cells under actual culture conditions as well as under the flow conditions on the arteriolar wall showed that there is a strong dependence of the local wall stress (WSS) distribution on the cellular shape factors and the cellular alignment. The present study simulated spontaneous random motions of the endothelial cells under actual culture conditions, and found that the endothelial cells aligned to the flow direction to reduce the wall shear stress at the summit of the cells.

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Spontaneous alignment of a three-dimensional model of cultured endothelial cells under steady flow condition investigated using computational fluid mechanics

Abstract

Other

ASJC Scopus subject areas

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