Spectroscopic studies on a novel intramolecular hydrogen bond within the (6-4) photoproduct.

Junpei Yamamoto, Yoshiyuki Tanaka, Kenichi Hitomi, Elizabeth D. Getzoff, Shigenori Iwai

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The (6-4) photoproduct, which is one of major UV-induced lesions formed between adjacent pyrimidine bases in DNA, was characterized by using (15)N NMR, fluorescence emission, and UV/VIS absorption at various pH values. From these experiments, we identified a novel intramolecular hydrogen bond between the hydroxyl group at the C5 position of the 5' component and the N3 of the 3' pyrimidone ring within the (6-4) photoproduct.

Original languageEnglish
Pages (from-to)79-80
Number of pages2
JournalNucleic acids symposium series (2004)
Issue number51
Publication statusPublished - 2007 Jan 1

ASJC Scopus subject areas

  • Medicine(all)

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    Yamamoto, J., Tanaka, Y., Hitomi, K., Getzoff, E. D., & Iwai, S. (2007). Spectroscopic studies on a novel intramolecular hydrogen bond within the (6-4) photoproduct. Nucleic acids symposium series (2004), (51), 79-80.