TY - JOUR
T1 - Spectroscopic analyses of DNA duplexes in the presence of mercury ions.
AU - Yamaguchi, Hiroshi
AU - Oda, Shuji
AU - Kojima, Chojiro
AU - Ono, Akira
AU - Kondo, Yoshinori
AU - Tanaka, Yoshiyuki
N1 - Copyright:
This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine
PY - 2005
Y1 - 2005
N2 - The DNA duplex with tandem T x T mismatches in the presence of Hg(II) has been studied by NMR spectroscopy. For this study, we synthesized decamer duplex with two successive T x T mismatches (TT10). From two-dimensional (2D) 1H-1H NOESY spectrum of TT10 in complex with Hg(II), we were able to trace sequential NOE walks between base protons and anomeric protons (H1'), and assigned all of them. Based on these assignments and NOESY spectra, we could assigned all the non-exchangeable protons of TT10 in the presence of Hg(II).
AB - The DNA duplex with tandem T x T mismatches in the presence of Hg(II) has been studied by NMR spectroscopy. For this study, we synthesized decamer duplex with two successive T x T mismatches (TT10). From two-dimensional (2D) 1H-1H NOESY spectrum of TT10 in complex with Hg(II), we were able to trace sequential NOE walks between base protons and anomeric protons (H1'), and assigned all of them. Based on these assignments and NOESY spectra, we could assigned all the non-exchangeable protons of TT10 in the presence of Hg(II).
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U2 - 10.1093/nass/49.1.199
DO - 10.1093/nass/49.1.199
M3 - Article
C2 - 17150702
AN - SCOPUS:33747625618
SP - 199
EP - 200
JO - Nucleic acids symposium series (2004)
JF - Nucleic acids symposium series (2004)
SN - 1746-8272
IS - 49
ER -