Spectral Assignments and Reference Data Complete1H and13C resonance assignments of glycosidic conjugates of non-amidated and amidated bile acids

Takashi Iida, Yuka Kasuga, Masayuki Arakawa, Kumiko Mushiake, Shigeo Ikegawa, Junichi Goto, Toshio Nambara

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Complete 1H and 13C resonance assignments on the basis of ID and 2D NMR were made for seven naturally occurring variants of the 3α-, 6α- and 7β-O-β-D-glycosidic conjugates (glucosides, N-acetylglucosaminides and glucuronides) of non-amidated and glycine- and taurine-amidated bile acids related to lithocholic, hyodeoxycholic, chenodeoxycholic, ursodeoxycolic, deoxycholic and cholic acids. The 1H and 13C NMR signals serving to characterize each of the glycosidic conjugates of bile acids and the effects of the O-β-D-glucosidation, O-β-D-N-acetylglucosaminidation and O-β-D-glucuronidation at the 3-, 6- or 7-position in the 5β-steroid nucleus on the 1H and 13C resonances were clarified and used in the structural elucidation of these bile acid glycosides.

Original languageEnglish
Pages (from-to)749-756
Number of pages8
JournalMagnetic Resonance in Chemistry
Volume39
Issue number12
DOIs
Publication statusPublished - 2001 Jan 1

Keywords

  • Bile acid N-acetylglucosaminides
  • Bile acid glucosides
  • Bile acid glucuronides
  • Bile acid glycosides
  • C NMR
  • Glycine-conjugated bile acids
  • H NMR
  • NMR
  • Taurine-conjugated bile acids
  • Two-dimensional NMR

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)

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