SPECT collimator dependency of scatter and validation of transmission dependent scatter compensation methodologies

K. M. Kim, H. Watabe, M. Shidahara, H. Iida

Research output: Contribution to conferencePaperpeer-review


Scatter correction is important for absolute quantification in SPECT. Among the approaches taken to achieve scatter correction, some methods using transmission information for scatter estimation requires the scatter models based on the physical characteristics of the scattered photons. The influence of the SPECT collimator on the characteristics of the scattered photon, however, has not been well studied yet. In this study, we investigated the relationship between scatter and collimator design for the use of the transmission-dependent convolution subtraction (TDCS) method. Monte-Carlo simulations with various collimator acceptance angles and experiments with 4 collimators of 2 SPECT cameras were performed to obtain the scatter fraction (SF) and the line-spread function (LSF) of Tc-99m. The experiments with I-123 also used 6 collimators of 3 SPECT systems to obtain the SF and the LSF. In the simulations, the SF of Tc-99m did not change with the collimator acceptance angles. The LSFs measured for Tc-99m showed an excellent agreement between collimators. In the experiments for I-123. the SF was practically the same for the 6 collimators, although a small difference could be observed, due to the septal penetration. Also, the shape of the LSF was very similar between the collimators. These results reveal that scatter is independent of SPECT collimator design for Tc-99m and even I-123. and that the TDCS could be applicable to scatter correction of I-123 using a unique collimator-independent set of parameters. Detailed instructions are given for preparing manuscripts in camera-ready format for publication in a Conference Issue of the Transactions on Nuclear Science. Papers published in Conference Issues are reproduced directly from the manuscript prepared by the author.

Original languageEnglish
Publication statusPublished - 2000
Externally publishedYes
Event2000 IEEE Nuclear Science Symposium Conference Record - Lyon, France
Duration: 2000 Oct 152000 Oct 20


Other2000 IEEE Nuclear Science Symposium Conference Record

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'SPECT collimator dependency of scatter and validation of transmission dependent scatter compensation methodologies'. Together they form a unique fingerprint.

Cite this