TY - JOUR
T1 - Specificity and sensitivity of glaucoma detection in the Japanese population using scanning laser polarimetry
AU - Funaki, Shigeo
AU - Shirakashi, Motohiro
AU - Yaoeda, Kiyoshi
AU - Abe, Haruki
AU - Kunimatsu, Shiho
AU - Suzuki, Yasuyuki
AU - Tomita, Goji
AU - Araie, Makoto
AU - Yamada, Noriko
AU - Uchida, Hideya
AU - Yamamoto, Tetsuya
AU - Kitazawa, Yoshiaki
PY - 2002
Y1 - 2002
N2 - Aims: To investigate the usefulness of the scanning laser polarimeter (GDx; GDx Nerve Fiber Analyzer) for glaucoma detection in the Japanese population, and to investigate the difference in the thickness of retinal nerve fibre layer (RNFL) between normal tension glaucoma (NTG) and primary open angle glaucoma (POAG). Methods: 69 eyes of 69 normal subjects and 115 eyes of 115 chronic open angle glaucoma patients (60 NTG and 55 POAG patients) were studied. The thickness of RNFL was measured with GDx. An eye was diagnosed as glaucomatous, if at least one original GDx varioble showed p <5%. The difference in thickness of RNFL between the NTG and POAG groups was then investigated. Results: 46 normal eyes (66.7%) were diagnosed as not glaucomatous (no variables showing p <5%), and 93 glaucomatous eyes (46 NTG and 47 POAG eyes) (80.9%) were diagnosed as glaucomatous. Actual values of average thickness, ellipse average, superior average, and superior integral were significantly lower in the POAG group than those in the NTG group. Conclusions: New variables which elucidate focal RNFL defects or early changes are needed to improve the moderate detection ability found in this present study. The pattern of the change in RNFL may differ in NTG and POAG groups.
AB - Aims: To investigate the usefulness of the scanning laser polarimeter (GDx; GDx Nerve Fiber Analyzer) for glaucoma detection in the Japanese population, and to investigate the difference in the thickness of retinal nerve fibre layer (RNFL) between normal tension glaucoma (NTG) and primary open angle glaucoma (POAG). Methods: 69 eyes of 69 normal subjects and 115 eyes of 115 chronic open angle glaucoma patients (60 NTG and 55 POAG patients) were studied. The thickness of RNFL was measured with GDx. An eye was diagnosed as glaucomatous, if at least one original GDx varioble showed p <5%. The difference in thickness of RNFL between the NTG and POAG groups was then investigated. Results: 46 normal eyes (66.7%) were diagnosed as not glaucomatous (no variables showing p <5%), and 93 glaucomatous eyes (46 NTG and 47 POAG eyes) (80.9%) were diagnosed as glaucomatous. Actual values of average thickness, ellipse average, superior average, and superior integral were significantly lower in the POAG group than those in the NTG group. Conclusions: New variables which elucidate focal RNFL defects or early changes are needed to improve the moderate detection ability found in this present study. The pattern of the change in RNFL may differ in NTG and POAG groups.
UR - http://www.scopus.com/inward/record.url?scp=0036146896&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036146896&partnerID=8YFLogxK
U2 - 10.1136/bjo.86.1.70
DO - 10.1136/bjo.86.1.70
M3 - Article
C2 - 11801507
AN - SCOPUS:0036146896
VL - 86
SP - 70
EP - 74
JO - British Journal of Ophthalmology
JF - British Journal of Ophthalmology
SN - 0007-1161
IS - 1
ER -