Specification of auditory sensitivity by Drosophila TRP channels

Martin C. Göpfert, Jörg T. Albert, B. Nadrowski, A. Kamikouchi

Research output: Contribution to journalArticle

107 Citations (Scopus)

Abstract

Ears achieve their exquisite sensitivity by means of mechanical feedback: motile mechanosensory cells through their active motion boost the mechanical input from the ear. Examination of the auditory mechanics in Drosophila melanogaster mutants shows that the transient receptor potential (TRP) channel NompC is required to promote this feedback, whereas the TRP vanilloid (TRPV) channels Nan and Iav serve to control the feedback gain. The combined function of these channels specifies the sensitivity of the fly auditory organ.

Original languageEnglish
Pages (from-to)999-1000
Number of pages2
JournalNature Neuroscience
Volume9
Issue number8
DOIs
Publication statusPublished - 2006 Aug 1
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)

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