Species barrier prevents an abnormal isoform of prion protein from accumulating in follicular dendritic cells of mice with Creutzfeldt-Jakob disease

T. Muramoto, T. Kitamoto, M. Z. Hoque, J. Tateishi, I. Goto

Research output: Contribution to journalComment/debatepeer-review

22 Citations (Scopus)

Abstract

The accumulation of abnormal prion protein in follicular dendritic cells did not occur in mice inoculated with materials from human Creutzfeldt-Jakob disease, whereas it always occurred in mice inoculated with mouse-adapted agents, suggesting an intense expression of the species barrier in the lymphoreticular system.

Original languageEnglish
Pages (from-to)6808-6810
Number of pages3
JournalJournal of virology
Volume67
Issue number11
DOIs
Publication statusPublished - 1993

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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