SOS induction in Escherichia coli by single-stranded DNA of mutant filamentous phage: Monitoring by cleavage of LexA repressor

N. Higashitani, A. Higashitani, K. Horiuchi

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Infection of Escherichia coli in the presence of chloramphenicol with mutant filamentous phage that are defective in the initiation of minus- strand DNA synthesis induces the SOS response as monitored by cellular LexA levels. This observation demonstrates that single-stranded DNA serves as a primary signal for SOS induction in vivo.

Original languageEnglish
Pages (from-to)3610-3612
Number of pages3
JournalJournal of bacteriology
Volume177
Issue number12
DOIs
Publication statusPublished - 1995

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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