Sonodynamically induced effect of eosin Y on isolated sarcoma 180 cells

N. Yumita, S. I. Umemura

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Sarcoma 180 cells were suspended in air-saturated PBS and exposed to standing-wave ultrasound for up to 60 seconds in the presence and absence of eosin Y (EY). Rate of ultrasound-induced cell damage was enhanced two to three times with 160 μM EY, while no cell damage was observed with EY alone. Histidine significantly inhibited this enhancement, possibly suggesting a sonochemical mechanism.

Original languageEnglish
Pages (from-to)11-16
Number of pages6
JournalJournal of Medical Ultrasonics
Issue number1
Publication statusPublished - 1999 Apr 22


  • Cell damage
  • Eosin Y
  • Sarcoma 180
  • Sonochemical mechanism
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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