Solubilization and functional changes of biomolecules in ionic liquids

Masahiro Goto, Kojiro Shimojo, Kazunori Nakashima

Research output: Contribution to conferencePaper

Abstract

This lecture reports on the protein transfer from an aqueous phase into ionic liquids (ILs) with dicyclohexano-18-crown-6 (DCH18C6), and the functional change of cytochrome c (Cyt-c) dissolved in ILs. Further, a protein is modified with comb-shaped poly (ethylene glycol), PM13. PM13 modified subtilisin (PM13-Sub) could be solubilized clearly in a wide range of pure ILs. This markedly high activity in the IL was superior to that in organic solvents commonly used for enzymatic catalysis. PM13-Sub was also found to retain its catalytic activity in the ILs for a prolonged period.

Original languageEnglish
Pages4176-4177
Number of pages2
Publication statusPublished - 2006 Dec 1
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: 2006 Sep 202006 Sep 22

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
CountryJapan
CityToyama
Period06/9/2006/9/22

Keywords

  • Biotransformation /
  • Dissolution
  • Enzymatic reaction
  • Ionic liquids
  • Protein
  • Solubilization

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Goto, M., Shimojo, K., & Nakashima, K. (2006). Solubilization and functional changes of biomolecules in ionic liquids. 4176-4177. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.