Solid phase synthesis of heterocyclic compounds

Yoshinori Kondo; Hisashi Shinkai; Ken Ichi Tanji

doi:10.5059/yukigoseikyokaishi.56.2

Solid phase synthesis of heterocyclic compounds

Yoshinori Kondo, Hisashi Shinkai, Ken Ichi Tanji

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Recent developments and current situation of solid phase heterocyclic synthesis are discussed focussing on cyclization of heterocyclic compounds. Solid phase synthesis is regarded as a basic technology for supporting combinatorial synthesis and automated synthesis. Heterocyclic compounds have been found in many biologically active substances and further investigation of solid phase heterocyclic chemistry is desired.

Original language	English
Pages (from-to)	2-10
Number of pages	9
Journal	Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
Volume	56
Issue number	1
DOIs	https://doi.org/10.5059/yukigoseikyokaishi.56.2
Publication status	Published - 1998 Jan

Keywords

Automated synthesis
Combinatorial chemistry
Cyclization
Heterocyclic compounds
Medicinal chemistry
Solid phase synthesis

ASJC Scopus subject areas

Organic Chemistry

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title = "Solid phase synthesis of heterocyclic compounds",

abstract = "Recent developments and current situation of solid phase heterocyclic synthesis are discussed focussing on cyclization of heterocyclic compounds. Solid phase synthesis is regarded as a basic technology for supporting combinatorial synthesis and automated synthesis. Heterocyclic compounds have been found in many biologically active substances and further investigation of solid phase heterocyclic chemistry is desired.",

keywords = "Automated synthesis, Combinatorial chemistry, Cyclization, Heterocyclic compounds, Medicinal chemistry, Solid phase synthesis",

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AU - Kondo, Yoshinori

AU - Shinkai, Hisashi

AU - Tanji, Ken Ichi

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AB - Recent developments and current situation of solid phase heterocyclic synthesis are discussed focussing on cyclization of heterocyclic compounds. Solid phase synthesis is regarded as a basic technology for supporting combinatorial synthesis and automated synthesis. Heterocyclic compounds have been found in many biologically active substances and further investigation of solid phase heterocyclic chemistry is desired.

KW - Automated synthesis

KW - Combinatorial chemistry

KW - Cyclization

KW - Heterocyclic compounds

KW - Medicinal chemistry

KW - Solid phase synthesis

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