SnCl4-promoted ethenylation reaction of hydroxylated heteroarenes

Kensuke Akamatsu; Ryo Amemiya; Masahiko Yamaguchi

SnCl₄-promoted ethenylation reaction of hydroxylated heteroarenes

Kensuke Akamatsu, Ryo Amemiya, Masahiko Yamaguchi

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Reaction of hydroxylated heteroarenes and acetylene in the presence of SnCl₄ and Bu₃N (or Et₃N) gives the corresponding ethenylated arenes. The reaction takes place at the neighboring position of the hydroxy group, and is applicable to quinolines, an isoquinoline, pyridines, and N-trifluoromethanesulfonylated indoles provided that the optimized conditions for the ethenylation and workup are employed.

Original language	English
Pages (from-to)	1839-1847
Number of pages	9
Journal	Heterocycles
Volume	63
Issue number	8
Publication status	Published - 2004 Aug 1

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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title = "SnCl4-promoted ethenylation reaction of hydroxylated heteroarenes",

abstract = "Reaction of hydroxylated heteroarenes and acetylene in the presence of SnCl4 and Bu3N (or Et3N) gives the corresponding ethenylated arenes. The reaction takes place at the neighboring position of the hydroxy group, and is applicable to quinolines, an isoquinoline, pyridines, and N-trifluoromethanesulfonylated indoles provided that the optimized conditions for the ethenylation and workup are employed.",

author = "Kensuke Akamatsu and Ryo Amemiya and Masahiko Yamaguchi",

year = "2004",

month = aug,

day = "1",

language = "English",

volume = "63",

pages = "1839--1847",

journal = "Heterocycles",

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publisher = "Japan Institute of Heterocyclic Chemistry",

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T1 - SnCl4-promoted ethenylation reaction of hydroxylated heteroarenes

AU - Akamatsu, Kensuke

AU - Amemiya, Ryo

AU - Yamaguchi, Masahiko

PY - 2004/8/1

Y1 - 2004/8/1

N2 - Reaction of hydroxylated heteroarenes and acetylene in the presence of SnCl4 and Bu3N (or Et3N) gives the corresponding ethenylated arenes. The reaction takes place at the neighboring position of the hydroxy group, and is applicable to quinolines, an isoquinoline, pyridines, and N-trifluoromethanesulfonylated indoles provided that the optimized conditions for the ethenylation and workup are employed.

AB - Reaction of hydroxylated heteroarenes and acetylene in the presence of SnCl4 and Bu3N (or Et3N) gives the corresponding ethenylated arenes. The reaction takes place at the neighboring position of the hydroxy group, and is applicable to quinolines, an isoquinoline, pyridines, and N-trifluoromethanesulfonylated indoles provided that the optimized conditions for the ethenylation and workup are employed.

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M3 - Article

AN - SCOPUS:4043174062

VL - 63

SP - 1839

EP - 1847

JO - Heterocycles

JF - Heterocycles

SN - 0385-5414

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