Small cell carcinoma of the bladder

Makoto Satoh, Seiichi Orikasa, Sadafumi Kawamura, Chikara Ohyama, Seiichi Saitoh, Yutaka Chiba, Hiroo Ishikawa, Yoshiki Mikami, Ryou Ichinohazama, Sen ichiroh Hakomori

Research output: Contribution to journalArticlepeer-review


A 61-year-old male visited us with chief complaints of macroscopic hematuria and bladder irritation symptons. Cystoscope, U/S, MRI, and CT showed an extensive non-papillary, wide-based tumor centering around the anterior wall of the bladder. Transabdominal U/S-guided full-thickness biopsy indicated a pT3a (Biopsy) primary small cell carcinoma of the bladder containing neuroendocrine granules. Immunohistochemical studies revealed Fuc GM1, an antigen related to small cell carcinoma of the lung. Neoadjuvant therapy consisted of preoperative irradiation at 50 Gy and intraarteial infusion chemotherapy with CDDP and THP. Since a follow-up full thickness biopsy indicated pTO (Biopsy), total cystectomy was performed. Examination of the resected specimen also indicated pathological CR.

Original languageEnglish
Pages (from-to)2094-2097
Number of pages4
JournalJapanese Journal of Urology
Issue number12
Publication statusPublished - 1992


  • Fucosyl GM1 ganglioside
  • neoadjuvant therapy
  • small cell carcinoma of bladder

ASJC Scopus subject areas

  • Urology


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