Site specific analysis of anionic lipid by membrane surface-enhanced raman spectroscopy with different sized gold nanoparticles

Miftah Faried, Seiya Ando, Keishi Suga, Yukihiro Okamoto, Hiroshi Umakoshi

Research output: Contribution to journalArticlepeer-review

Abstract

For highly sensitive analysis of anionic lipid membranes, we developed membrane surface enhanced Raman spectroscopy with different sized gold nanoparticles (AuNPs). The employed AuNPs did not disturb and retained native lipid membrane properties such as fluidity and polarity, and enhanced Raman signals of anionic lipid membrane. Furthermore, the enhanced part of lipid membrane was modulated by different size AuNPs. Thus, our method enables site specific analysis of anionic lipid membrane in high sensitive manner keeping native lipid membrane properties.

Original languageEnglish
Pages (from-to)1107-1110
Number of pages4
JournalChemistry Letters
Volume49
Issue number9
DOIs
Publication statusPublished - 2020 Jun

Keywords

  • Anionic lipid
  • Gold nanoparticle
  • Membrane surface enhanced Raman spectroscopy

ASJC Scopus subject areas

  • Chemistry(all)

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