Site specific analysis of anionic lipid by membrane surface-enhanced raman spectroscopy with different sized gold nanoparticles

Miftah Faried; Seiya Ando; Keishi Suga; Yukihiro Okamoto; Hiroshi Umakoshi

doi:10.1246/cl.200389

Site specific analysis of anionic lipid by membrane surface-enhanced raman spectroscopy with different sized gold nanoparticles

Miftah Faried, Seiya Ando, Keishi Suga, Yukihiro Okamoto, Hiroshi Umakoshi

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

For highly sensitive analysis of anionic lipid membranes, we developed membrane surface enhanced Raman spectroscopy with different sized gold nanoparticles (AuNPs). The employed AuNPs did not disturb and retained native lipid membrane properties such as fluidity and polarity, and enhanced Raman signals of anionic lipid membrane. Furthermore, the enhanced part of lipid membrane was modulated by different size AuNPs. Thus, our method enables site specific analysis of anionic lipid membrane in high sensitive manner keeping native lipid membrane properties.

Original language	English
Pages (from-to)	1107-1110
Number of pages	4
Journal	Chemistry Letters
Volume	49
Issue number	9
DOIs	https://doi.org/10.1246/cl.200389
Publication status	Published - 2020 Jun
Externally published	Yes

Keywords

Anionic lipid
Gold nanoparticle
Membrane surface enhanced Raman spectroscopy

ASJC Scopus subject areas

Chemistry(all)

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10.1246/cl.200389

Cite this

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title = "Site specific analysis of anionic lipid by membrane surface-enhanced raman spectroscopy with different sized gold nanoparticles",

abstract = "For highly sensitive analysis of anionic lipid membranes, we developed membrane surface enhanced Raman spectroscopy with different sized gold nanoparticles (AuNPs). The employed AuNPs did not disturb and retained native lipid membrane properties such as fluidity and polarity, and enhanced Raman signals of anionic lipid membrane. Furthermore, the enhanced part of lipid membrane was modulated by different size AuNPs. Thus, our method enables site specific analysis of anionic lipid membrane in high sensitive manner keeping native lipid membrane properties.",

keywords = "Anionic lipid, Gold nanoparticle, Membrane surface enhanced Raman spectroscopy",

author = "Miftah Faried and Seiya Ando and Keishi Suga and Yukihiro Okamoto and Hiroshi Umakoshi",

note = "Funding Information: M.F thanks Dr. Tham Thi Bui and Mr. Arun Ajaikumar for the constructive comments and technical support. M.F. expresses his most grateful for support from the Japanese Government (Monbukagakusho: MEXT) scholarship while completing this study. This research was supported by a Grant-in-Aid for Scientific Research (A) (26249116), Scientific Research B (18H02005), The Watanabe Foundation, and International Joint Research Promotion Program of Osaka University. Publisher Copyright: {\textcopyright} 2020 The Chemical Society of Japan.",

year = "2020",

month = jun,

doi = "10.1246/cl.200389",

language = "English",

volume = "49",

pages = "1107--1110",

journal = "Chemistry Letters",

issn = "0366-7022",

publisher = "Chemical Society of Japan",

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AU - Faried, Miftah

AU - Ando, Seiya

AU - Suga, Keishi

AU - Okamoto, Yukihiro

AU - Umakoshi, Hiroshi

N1 - Funding Information: M.F thanks Dr. Tham Thi Bui and Mr. Arun Ajaikumar for the constructive comments and technical support. M.F. expresses his most grateful for support from the Japanese Government (Monbukagakusho: MEXT) scholarship while completing this study. This research was supported by a Grant-in-Aid for Scientific Research (A) (26249116), Scientific Research B (18H02005), The Watanabe Foundation, and International Joint Research Promotion Program of Osaka University. Publisher Copyright: © 2020 The Chemical Society of Japan.

PY - 2020/6

Y1 - 2020/6

N2 - For highly sensitive analysis of anionic lipid membranes, we developed membrane surface enhanced Raman spectroscopy with different sized gold nanoparticles (AuNPs). The employed AuNPs did not disturb and retained native lipid membrane properties such as fluidity and polarity, and enhanced Raman signals of anionic lipid membrane. Furthermore, the enhanced part of lipid membrane was modulated by different size AuNPs. Thus, our method enables site specific analysis of anionic lipid membrane in high sensitive manner keeping native lipid membrane properties.

AB - For highly sensitive analysis of anionic lipid membranes, we developed membrane surface enhanced Raman spectroscopy with different sized gold nanoparticles (AuNPs). The employed AuNPs did not disturb and retained native lipid membrane properties such as fluidity and polarity, and enhanced Raman signals of anionic lipid membrane. Furthermore, the enhanced part of lipid membrane was modulated by different size AuNPs. Thus, our method enables site specific analysis of anionic lipid membrane in high sensitive manner keeping native lipid membrane properties.

KW - Anionic lipid

KW - Gold nanoparticle

KW - Membrane surface enhanced Raman spectroscopy

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JF - Chemistry Letters

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IS - 9

ER -

Site specific analysis of anionic lipid by membrane surface-enhanced raman spectroscopy with different sized gold nanoparticles

Abstract

Keywords

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