Singular value decomposition of received ultrasound signal to separate tissue, blood flow, and cavitation signals

Hayato Ikeda, Ryo Nagaoka, Maxime Lafond, Shin Yoshizawa, Ryosuke Iwasaki, Moe Maeda, Shinichiro Umemura, Yoshifumi Saijo

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

High-intensity focused ultrasound is a noninvasive treatment applied by externally irradiating ultrasound to the body to coagulate the target tissue thermally. Recently, it has been proposed as a noninvasive treatment for vascular occlusion to replace conventional invasive treatments. Cavitation bubbles generated by the focused ultrasound can accelerate the effect of thermal coagulation. However, the tissues surrounding the target may be damaged by cavitation bubbles generated outside the treatment area. Conventional methods based on Doppler analysis only in the time domain are not suitable for monitoring blood flow in the presence of cavitation. In this study, we proposed a novel filtering method based on the differences in spatiotemporal characteristics, to separate tissue, blood flow, and cavitation by employing singular value decomposition. Signals from cavitation and blood flow were extracted automatically using spatial and temporal covariance matrices.

Original languageEnglish
Article number07LF04
JournalJapanese journal of applied physics
Volume57
Issue number7
DOIs
Publication statusPublished - 2018 Jul

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

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