Single neural cells on mobile microplates for precise neural network assembly

Shotaro Yoshida, T. Teshima, K. Kuribayashi-Shigetomi, S. Takeuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Citations (Scopus)

Abstract

This paper describes a method to assemble single neural cells into neural networks by utilizing microfabricated mobile microplates. Single neural cells were cultured on the mobile microplates. Directions of their neurite growth were controlled by guidepaths attached beside the microplates. We demonstrated that single neural cells with directed neurites were moved and assembled by mobile microplates into desired network structure, and also the network geometry was redefined. We believe this modular assembly method could be applied to precise patterning of neural networks, and also useful in basic studies of single-cell-level neural networks.

Original languageEnglish
Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Pages1749-1751
Number of pages3
Volume3
Publication statusPublished - 2011 Dec 1
Externally publishedYes
Event15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
Duration: 2011 Oct 22011 Oct 6

Other

Other15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
CountryUnited States
CitySeattle, WA
Period11/10/211/10/6

Keywords

  • Microplate
  • Modular assembly
  • Parylene
  • Single-cell-level neural network

ASJC Scopus subject areas

  • Control and Systems Engineering

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