Simultaneous observation of cavitation bubbles generated in biological tissue by high-speed optical and acoustic imaging methods

Kai Suzuki, Ryosuke Iwasaki, Ryo Takagi, Shin Yoshizawa, Shin Ichiro Umemura

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Acoustic cavitation bubbles are useful for enhancing the heating effect in high-intensity focused ultrasound (HIFU) treatment. Many studies were conducted to investigate the behavior of such bubbles in tissue-mimicking materials, such as a transparent gel phantom; however, the detailed behavior in tissue was still unclear owing to the difficulty in optical observation. In this study, a new biological phantom was developed to observe cavitation bubbles generated in an optically shallow area of tissue. Two imaging methods, high-speed photography using light scattering and highspeed ultrasonic imaging, were used for detecting the behavior of the bubbles simultaneously. The results agreed well with each other for the area of bubble formation and the temporal change in the region of bubbles, suggesting that both methods are useful for visualizing the bubbles.

Original languageEnglish
Article number07JF27
JournalJapanese journal of applied physics
Volume56
Issue number7
DOIs
Publication statusPublished - 2017 Jul

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

Fingerprint Dive into the research topics of 'Simultaneous observation of cavitation bubbles generated in biological tissue by high-speed optical and acoustic imaging methods'. Together they form a unique fingerprint.

Cite this