Simultaneous measurement of vibrations on the arterial wall downstream and upstream from an atherosclerotic lesions

Kazuhiro Sunagawa, Hiroshi Kanai, Yoshiro Koiwa, Keiko Nitta, Motonao Tanaka

Research output: Contribution to journalConference articlepeer-review

5 Citations (Scopus)

Abstract

In the literature, it has been reported that cerebral ischemia paroxysm and cerebral infarctions occurs with high percentages when the inner diameter is decreased less than 70% due to a stenosis. The most primary reason of these events is rupture of atherosclerotic plaques of the carotid artery. However, it is difficult to noninvasively predict the rupture. For solving this problem, we have investigated the influence of blood flow on the atherosclerotic plaque by transcutaneously measuring small vibrations caused by the pulsatile flow on the arterial wall. In this paper, small vibrations on the carotid arterial wall are measured and analyzed for patients with atherosclerosis and for healthy subjects. From in vivo experimental results, high frequency components were present in the resultant small vibrations on the wall of downstream from the atherosclerotic plaque. Moreover, from experiments using a silicone tube with small pressure sensors, it is found that there is close relationship between the vibrations and inner pressure for both cases with and without an artificial stenosis. These results might open the possibility to predict rupture of atherosclerotic plaques in future by measuring the small vibrations arterial wall.

Original languageEnglish
Pages (from-to)1507-1510
Number of pages4
JournalProceedings of the IEEE Ultrasonics Symposium
Volume2
Publication statusPublished - 1999 Dec 1
Event1999 IEEE Ultrasonics Symposium - Caesars Tahoe, NV, USA
Duration: 1999 Oct 171999 Oct 20

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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