Simulation study on hierarchical information processing on the active neuronal dendrites

Norihiro Katayama, Mitsuyuki Nakao, Yoshinari Mizutani, Mitsuaki Yamamoto

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Dynamics of a pyramidal neuron in hippocampus (CA3 neuron) is modeled in a discrete form based on physiological findings, which is known to involve dendritic calcium-activated dynamics. Responses of the CA3 neuron model to excitatory stimulus on the apical dendrites is studied under the varied somatic inhibition. Computer simulations show the following phenomena: The CA3 neuron model behaves in the spatially cooperative manner under the weak somatic inhibition. On the other hand, when the somatic inhibition is strong, dendritic activities are forced to be localized. These results suggest that proximal dendrite branches could control the dendritic interaction among more distal ones. Highly organized neuronal information processing might be possible by the cooperation of the hierarchically interacting dendrite system and the distribution pattern of synapses on it.

Original languageEnglish
Title of host publicationProceedings of the International Joint Conference on Neural Networks
PublisherPubl by IEEE
Pages123-126
Number of pages4
ISBN (Print)0780314212, 9780780314214
Publication statusPublished - 1993 Dec 1
EventProceedings of 1993 International Joint Conference on Neural Networks. Part 1 (of 3) - Nagoya, Jpn
Duration: 1993 Oct 251993 Oct 29

Publication series

NameProceedings of the International Joint Conference on Neural Networks
Volume1

Other

OtherProceedings of 1993 International Joint Conference on Neural Networks. Part 1 (of 3)
CityNagoya, Jpn
Period93/10/2593/10/29

ASJC Scopus subject areas

  • Software
  • Artificial Intelligence

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