Simple synthesis of α-hydroxyamino carbonyl compounds: New scope of the nitroso aldol reaction

Norie Momiyama; Hisashi Yamamoto

doi:10.1021/ol026443k

Simple synthesis of α-hydroxyamino carbonyl compounds: New scope of the nitroso aldol reaction

Norie Momiyama, Hisashi Yamamoto

SCI - Chemistry

Research output: Contribution to journal › Article › peer-review

99 Citations (Scopus)

Abstract

(graph presented) The reaction of nitroso compounds with enolates, "the nitroso aldol reaction", occurs in high yield to generate α-hydroxyamino carbonyl compounds. Yields range from 42% to 98% with N-selectivity >99:1 from commercially available aromatic or aliphatic nitroso compounds and a variety of alkali metal or tin enolates.

Original language	English
Pages (from-to)	3579-3582
Number of pages	4
Journal	Organic letters
Volume	4
Issue number	21
DOIs	https://doi.org/10.1021/ol026443k
Publication status	Published - 2002 Oct 17

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol026443k

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title = "Simple synthesis of α-hydroxyamino carbonyl compounds: New scope of the nitroso aldol reaction",

abstract = "(graph presented) The reaction of nitroso compounds with enolates, {"}the nitroso aldol reaction{"}, occurs in high yield to generate α-hydroxyamino carbonyl compounds. Yields range from 42% to 98% with N-selectivity >99:1 from commercially available aromatic or aliphatic nitroso compounds and a variety of alkali metal or tin enolates.",

author = "Norie Momiyama and Hisashi Yamamoto",

year = "2002",

month = oct,

day = "17",

doi = "10.1021/ol026443k",

language = "English",

volume = "4",

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journal = "Organic Letters",

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T1 - Simple synthesis of α-hydroxyamino carbonyl compounds

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AU - Momiyama, Norie

AU - Yamamoto, Hisashi

PY - 2002/10/17

Y1 - 2002/10/17

N2 - (graph presented) The reaction of nitroso compounds with enolates, "the nitroso aldol reaction", occurs in high yield to generate α-hydroxyamino carbonyl compounds. Yields range from 42% to 98% with N-selectivity >99:1 from commercially available aromatic or aliphatic nitroso compounds and a variety of alkali metal or tin enolates.

AB - (graph presented) The reaction of nitroso compounds with enolates, "the nitroso aldol reaction", occurs in high yield to generate α-hydroxyamino carbonyl compounds. Yields range from 42% to 98% with N-selectivity >99:1 from commercially available aromatic or aliphatic nitroso compounds and a variety of alkali metal or tin enolates.

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M3 - Article

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JF - Organic Letters

SN - 1523-7060

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Simple synthesis of α-hydroxyamino carbonyl compounds: New scope of the nitroso aldol reaction

Abstract

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