The influence of age on the nocturnal fall in blood pressure (BP) was examined in essential hypertensive patients as well as normal subjects. BP was monitored every 5 min for 24 hr by means of a finger volume oscillometric device. Average daytime BP was similar in the 3 age groups [young : <40 (years), n=49, average daytime systolic BP (ASBP)=132±20 mmHg, average daytime diastolic BP (ADBP)= 82 ± 17 mmHg ; adult : 40≤ <60, n =110, ASBP =127 ± 19 mmHg, ADBP = 86 ± 13 mmHg ; old : 60≤, n=33, ASBP =131 ± 17 mmHg. ADBP = 83 ± 11, mean ± s.d.]. The nocturnal fall in BP was observed in all age groups and its amplitude (d B P = average daytime B P - average nighttime BP) in the old patients (ΔSBP = 13±11 mmHg, ΔDBP=10+8 mmHg) was similar to that in the young patients (ΔSBP=11±8 mmHg, ΔDBP=10±8 mmHg). The result suggests that information on the nocturnal behavior of BP is valuable in treating aged essential hypertensives to prevent cerebral and/or myocardial ischemia during sleep.
- ambulatory blood pressure monitoring
- circadian rhythm
- essential hypertension
- nocturnal fall in blood pressure
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)