Similarity in Amplitude of the Nocturnal fall in Blood Pressure in Old and Young Patients with Essential Hypertension

Minoru Nihei, Yutaka Imai, Keishi Abe, Shuichi Sasaki, Naoyoshi Minami, Masanori Munakata, Hiromichi Sakuma, Junichiro Hashimoto, Kaoru Yoshinaga, Hiroshi Sekino

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1 Citation (Scopus)

Abstract

The influence of age on the nocturnal fall in blood pressure (BP) was examined in essential hypertensive patients as well as normal subjects. BP was monitored every 5 min for 24 hr by means of a finger volume oscillometric device. Average daytime BP was similar in the 3 age groups [young : <40 (years), n=49, average daytime systolic BP (ASBP)=132±20 mmHg, average daytime diastolic BP (ADBP)= 82 ± 17 mmHg ; adult : 40≤ <60, n =110, ASBP =127 ± 19 mmHg, ADBP = 86 ± 13 mmHg ; old : 60≤, n=33, ASBP =131 ± 17 mmHg. ADBP = 83 ± 11, mean ± s.d.]. The nocturnal fall in BP was observed in all age groups and its amplitude (d B P = average daytime B P - average nighttime BP) in the old patients (ΔSBP = 13±11 mmHg, ΔDBP=10+8 mmHg) was similar to that in the young patients (ΔSBP=11±8 mmHg, ΔDBP=10±8 mmHg). The result suggests that information on the nocturnal behavior of BP is valuable in treating aged essential hypertensives to prevent cerebral and/or myocardial ischemia during sleep.

Original languageEnglish
Pages (from-to)163-169
Number of pages7
JournalTohoku Journal of Experimental Medicine
Volume158
Issue number2
DOIs
Publication statusPublished - 1989

Keywords

  • age
  • ambulatory blood pressure monitoring
  • circadian rhythm
  • essential hypertension
  • nocturnal fall in blood pressure

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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