Silent cerebral infarction: A potential risk for pneumonia in the elderly

T. Nakagawa, K. Sekizawa, K. Nakajoh, H. Tanji, H. Arai, Hidetada Sasaki

Research output: Contribution to journalArticlepeer-review

57 Citations (Scopus)

Abstract

Objective. To determine whether patients who have silent cerebral infarction are more likely to develop pneumonia than are controls without silent cerebral infarction. Design. We examined 269 community-residing participants of the senior day-care centre without history of previous stroke, and then followed them over a two-year period to assess pneumonia. On the basis of computerized tomography scans, they were divided into two groups: no infarction (n = 102) and cerebral hemispheric infarction (n = 167). Cerebral infarcts were further divided into deep and superficial infarcts. Results. The incidence of pneumonia was significantly higher in subjects with silent cerebral infarction (19.8%) than in controls (4.9%) (odds ratio, 4.67 [95% CI, 1.87-11.67]; P < 0.01). Deep infarcts were more closely associated with the incidence of pneumonia (29.1%) than superficial infarcts (7.6%) (odds ratio, 5.00 [CI, 1.91-13.08]; P < 0.01). Conclusions. Elderly subjects with silent cerebral infarction were more likely to develop pneumonia than were controls without silent cerebral infarction. Amongst hemispheric silent cerebral infarcts, those located in the deep brain structures may be an important predictor of the development of pneumonia.

Original languageEnglish
Pages (from-to)255-259
Number of pages5
JournalJournal of Internal Medicine
Volume247
Issue number2
DOIs
Publication statusPublished - 2000

Keywords

  • Cerebrovascular disorders
  • Cohort study
  • Epidemiology
  • Pneumonia
  • Risk factors
  • Silent aspiration

ASJC Scopus subject areas

  • Internal Medicine

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