Significance of urine dipstick test for occult blood in patients with diabetes mellitus

Noriko Ohisa, Katsumi Yoshida, Mitsuo Kaku, Yasushi Ishigaki, Yoshitomo Oka, Hiroshi Sato

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Objective: Hematuria is the usual urinary finding in patients with diabetic nephropathy. In this study, prevalence and significance of microhematuria in patients with diabetes mellitus were investigated. Material and methods: Five hundred and forty-two samples from outpatients, who consulted the Department of Diabetes and Metabolism, were categorized into 4 groups according to the results of the urine dipstick test. Group I: 258 samples, urinary protein (u-P) 1+ and occult blood (OB) negative, group II: 95 samples: u-P 1+, OB 1+∼3+, group III: 89 samples: u-P 2+∼3+, OB negative, group IV 100 samples u-P 2+∼3+, OB 1+∼3+. Results: Serum concentrations of creatinine and highly sensitive CRP were both significantly higher in group II than in group I. Those parameters were also significantly higher in group IV than in group III. Conclusions: These results indicate that a positive dipstick test for OB may occur in many patients with diabetes mellitus and suggest the progress of renal damage.

Original languageEnglish
Pages (from-to)664-668
Number of pages5
JournalJapanese Journal of Nephrology
Issue number7
Publication statusPublished - 2006


  • Diabetic nephropathy
  • Microalbuminuria
  • Microhematuria
  • Occult blood
  • Urinary protein

ASJC Scopus subject areas

  • Nephrology


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